DECOMPRESSIVE PATHOLOGY IN CETACEANS BASED ON AN EXPERIMENTAL PATHOLOGICAL MODEL



Treatment Approaches for Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide, and it is responsible for up to one million deaths annually.Although multiple risk factors for HCC have been identified, and despite preventive measures, the incidence of HCC continues to rise to epidemiologic proportions in the United States.In general, tumor resection and o

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Advancing studies on global biocrust distribution

Biological soil crusts (biocrusts hereafter) cover a substantial proportion of the dryland ecosystem and play crucial roles in ecological processes such as biogeochemical cycles, water distribution, and soil erosion.Consequently, studying the spatial distribution of biocrusts holds great significance for drylands, especially on a global scale, but

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Effects of pre-existing anti-adenovirus antibodies on transgene expression levels and therapeutic efficacies of arming oncolytic adenovirus

Abstract Oncolytic adenoviruses (OAds), most of which are based on species C human adenovirus serotype 5 (Ad5) (OAd5), have recently received much attention as potential anticancer agents.High seroprevalence of anti-Ad5 neutralizing antibodies is a major hurdle for Ad5-based gene therapy.However, the impacts of anti-Ad5 neutralizing antibodies on O

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